Physiology and Pharmacology Effects of Palmitoylethanolamide on Aqueous Humor Outflow
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چکیده
METHODS. The effects of PEA on outflow facility were measured using a porcine anterior segment–perfused organ culture model. The involvements of different receptors in PEA-induced changes were investigated using receptor antagonists and adenovirus delivered small hairpin RNAs (shRNAs). PEAinduced activation of p42/44 mitogen-activated protein kinase (MAPK) was determined by Western blot analysis using an antiphospho p42/44 MAPK antibody.
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تاریخ انتشار 2012